FIG 3.

United Kingdom regional RT078 phylogenies; Scotland and Oxfordshire. (A) Map and legend indicating the regions of Scotland and Oxfordshire from which genomes originated. The Scottish regions correspond to administrative areas known as “health boards.” (B) Time-scaled RT078 phylogeny for Scotland. Branch colors are as described in the panel A legend. Colored bars to the right of the phylogeny denote the ribosomal protection protein (RPP) allele sequences detected within each genome (as described in the Fig. 2 legend), numbers being assigned to identify distinct nucleotide sequences of tetM or tetO/32/O. Isolates were cultured from human clinical samples received from both hospital and community patients, the latter being indicated by a black dot. The gray shaded block over the region corresponding to the period prior to 1990 indicates that the region is not scaled identically for different phylogenies and should not be used for comparisons. (C) Time-scaled RT078 phylogeny for Oxfordshire clinical and nonclinical isolates. Branch colors are as described in the panel A legend. Colored bars indicate ribosomal protection protein alleles as described above.