Table 2.
Relative abundance of top 10 abundant families detected in NT and ASD groups and family presenting significant difference between NT and ASD groups.
| Family | Mean ± SD | Paired student t-test | Adjusted P* | FDR-corrected P | |
|---|---|---|---|---|---|
| ASD group | NT group | P | |||
| Bacteroidaceae | 31.57, 8.27 | 27.95, 11.84 | 0.105 | 0.421 | 0.532 |
| Prevotellaceae | 3.78, 7.16 | 4.64, 11.51 | 0.679 | 0.854 | 0.891 |
| Clostridia Clostridiales Lachnospiraceae | 23.69, 5.87 | 25.84, 8.52 | 0.162 | 0.160 | 0.361 |
| Ruminococcaceae | 22.34, 7.28 | 20.40, 6.67 | 0.245 | 0.079 | 0.285 |
| Fusobacteriaceae | 2.26, 6.79 | 1.03, 2.08 | 0.203 | 0.314 | 0.443 |
| Veillonellaceae | 0.94, 1.36 | 3.00, 6.33 | 0.021 | 0.107 | 0.309 |
| Bifidobacteriaceae | 3.07, 3.67 | 3.00, 2.91 | 0.925 | 0.791 | 0.837 |
| Porphyromonadaceae | 2.15, 1.16 | 2.70, 2.62 | 0.223 | 0.224 | 0.424 |
| Unidentified Firmicutes Clostridiales Lachnospiraceae | 1.22, 1.18 | 1.49, 2.16 | 0.497 | 0.415 | 0.532 |
| Rikenellaceae | 2.23, 1.92 | 2.26, 2.27 | 0.960 | 0.606 | 0.773 |
| Veillonellaceae | 0.94, 1.36 | 3.00, 6.33 | 0.021 | 0.107 | 0.309 |
| Pasteurellaceae | 0.65, 1.31 | 0.21, 0.42 | 0.038 | 0.064 | 0.257 |
| Enterobacteriaceae | 0.29, 0.29 | 0.78, 1.14 | 0.007 | 0.036 | 0.309 |
| Acidaminococcaceae | 0.16, 0.15 | 0.44, 0.48 | 0.001 | 0.002 | 0.029 |
| Desulfovibrionaceae | 0.09, 0.09 | 0.15, 0.14 | 0.040 | 0.036 | 0.201 |
| Lactobacillaceae | 0.01, 0.01 | 0.05, 0.12 | 0.024 | 0.036 | 0.201 |
ASD, autism spectrum disorders; NT, neurotypical. Relative abundance is shown as mean values (%) ± standard deviation (SD). P* value was adjusted for gestational age, delivery mode, parent educational levels, total energy, protein, fat, carbohydrate and fiber. Bold indicates P < 0.05.