. 2019 Mar 6;9:40. doi: 10.3389/fcimb.2019.00040

Table 3.

Relative abundance of top 10 abundant genera detected in NT and ASD groups and genera presenting significant difference between NT and ASD groups.

Genera	Mean ± SD		Paired Student t-test	Adjusted P^*	FDR-corrected P
	ASD group	NT group	P
Bacteroides	31.59, 8.28	27.98, 11.84	0.105	0.421	0.600
Prevotella subgroup 9	2.71, 6.54	4.42, 11.51	0.396	0.594	0.713
Fusobacterium	2.26, 6.79	1.03, 2.08	0.201	0.312	0.492
Megamonas	0.55, 0.99	2.51, 6.33	0.037	0.162	0.373
Faecalibacterium	13.99, 4.92	12.49, 5.23	0.225	0.081	0.294
Alloprevotella	0.28, 0.68	0.06, 0.19	0.048	0.059	0.249
Bifidobacterium	3.07, 3.67	3.00, 2.91	0.925	0.791	0.856
Pseudobutyrivibrio	4.63, 2.66	4.36, 3.57	0.623	0.453	0.622
Parabacteroides	1.64, 0.96	2.02, 2.31	0.312	0.288	0.477
Prevotellaceae NK3B31 group	0.30, 1.68	0.04, 0.13	0.297	0.443	0.612
Megamonas	0.55, 0.99	2.51, 6.33	0.037	0.162	0.373
Alloprevotella	0.28, 0.68	0.06, 0.19	0.048	0.059	0.249
Lachnoclostridium	2.25, 0.72	3.55, 1.92	2.85 × 10⁻⁴	1.54 × 10⁻⁴	0.005
Haemophilus	0.66, 1.31	0.22, 0.42	0.037	0.064	0.252
Escherichia-Shigella	0.18, 0.25	0.53, 0.81	0.010	0.043	0.216
Ruminiclostridium subgroup 6	0.01, 0.02	0.19, 0.61	0.050	0.092	0.317
Prevotella subgroup 2	0.26, 0.76	0.02, 0.04	0.045	0.109	0.324
Lachnospiraceae UCG-004	0.63, 0.51	0.44, 0.23	0.027	0.023	0.151
Tyzzerella subgroup 4	0.13, 0.08	0.50, 0.51	2.99 × 10⁻⁵	3.74 × 10⁻⁵	0.002
Phascolarctobacterium	0.16, 0.15	0.36, 0.42	0.007	0.014	0.123
Erysipelatoclostridium	0.04, 0.05	0.20, 0.37	0.009	0.004	0.067
Unidentified Ruminococcaceae	0.10, 0.06	0.18, 0.22	0.012	0.063	0.252
Eggerthella	0.02, 0.01	0.07, 0.13	0.017	0.013	0.123
Coprococcus subgroup 3	0.14, 0.09	0.21, 0.20	0.027	0.101	0.324
Odoribacter	0.12, 0.12	0.21, 0.17	0.009	0.009	0.111
Lactobacillus	0.01, 0.01	0.05, 0.13	0.024	0.036	0.196
Flavonifractor	0.08, 0.03	0.16, 0.11	7.14 × 10⁻⁶	2.75 × 10⁻⁵	0.002
Ruminococcaceae UCG-010	0.06, 0.09	0.03, 0.05	0.048	0.020	0.151
Unidentified Lachnospiraceae	0.06, 0.03	0.13, 0.11	4.14 × 10⁻⁵	6.12 × 10⁻⁵	0.002
Lachnospiraceae FCS020 group	0.12, 0.06	0.08, 0.06	4.26 × 10⁻⁴	0.005	0.070
Bilophila	0.05, 0.04	0.09, 0.06	0.003	0.004	0.057

ASD, autism spectrum disorders; NT, neurotypical. Relative abundance is shown as mean values (%), standard deviation (SD). P^* value was adjusted for gestational age, delivery mode, parent educational levels, total energy, protein, fat, carbohydrate and fiber. Bold indicates P < 0.05.