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Mucoadhesion time of mini-tablets containing 30 mg of Ch-EDTA, Ch-EDTA-cys or Ch-EDTA-cys-2MNA studied by rotating cylinder method using porcine intestinal mucosa. Ch: chitosan, cys: cysteine, 2MNA: 2-mercaptonicotinamide. (Mean ± SD, n = 5, * denotes statistical significant difference at p < 0.05). Reprinted from [138] with permission of Elsevier.
