. 2018 Jan 20;10(1):96. doi: 10.3390/polym10010096

Table 1.

Minimal inhibitory concentration against E. coli and S. aureus and hemolytic activity of functional polyglycidols with defined microstructures P(G^TMAPA₁₅-co-G^DDA₁₂) (5), P(G^APDEMA₁₆-co-G^DDA₁₁) (6), P(G^{DDAc, q})₂₇ (10), P(G^TMAPA₁₄-co-G^DDADDAc₁₃) (12).

		M_n,NMR ^a (g·mol⁻¹)	MIC₁₀₀ ^b,c (µg/mL)		HC₅₀ ^d (µg/mL)
Polymer	Microstructure		E. coli	S. aureus
5	P(G^TMAPA₁₅-co-G^DDA₁₂)	10,111	30	20	>>500 ^f
6	P(G^APDEMA₁₆-co-G^DDA₁₁)	9608	30	30	100
10	P(G^{DDAc, q})₂₇	18,947	30	>200	<10
12	P(G^TMAPA₁₄-co-G^DDADDAc₁₃)	13,476	200 ^d	>200‒500 ^e	<10

^a Molecular weight (M_n,NMR) calculated from ¹H NMR with an accuracy of integration of ±5%; ^b Minimum inhibitory concentration which prevents the visible growth of 100% of the bacteria within 20 h monitoring time; ^c Inoculum size = 1 × 10⁶–2 × 10⁶ CFU·mL⁻¹; ^d HC₅₀: concentration causing 50% lysis (hemolysis) of red blood cells (RBCs) relative to Triton X-100 (positive control, 100%), linear polyglycidol PG₂₇ (1) HC₅₀ >> 500 µg/mL; ^e Non-growth value due to turbidity of solution caused by the polymer; ^f 10–500 µg/mL of polymer 5 causing agglutination of RBC, and about 6% (at 10 µg/mL)–40% (at 500 µg/mL) hemolysis.