Table 1.
Sample | Tf-(PEGn-N3)x | Size (nm) b | Tf Amount per MNG (µg mg−1) c | CTC Capturing Efficiency (%) | |
---|---|---|---|---|---|
n | x a | ||||
MNG1 | - | - | 230 ± 90 | - | 13 |
MNG@Tf 1 | 4 | 1 | 160 ± 90 | 4 | 23 |
MNG@Tf 2 | 8 | 110 ± 90 | 2 | 33 | |
MNG@Tf 3 | 12 | 120 ± 60 | 2 | 23 | |
MNG@Tf 4 | 4 | 3 | 140 ± 70 | 4 | 64 |
MNG@Tf 5 | 8 | 110 ± 40 | 4 | 81 | |
MNG@Tf 6 | 12 | 130 ± 50 | 6 | 67 | |
MNG@Tf 7 | 4 | 5 | 150 ± 80 | 4 | 60 |
MNG@Tf 8 | 8 | 210 ± 80 | 4 | 65 | |
MNG@Tf 9 | 12 | 190 ± 70 | 2 | 58 | |
MNG@Tf 10 | 4 | 9 | 170 ± 90 | 2 | 50 |
MNG@Tf 11 | 8 | 160 ± 40 | 2 | 35 | |
MNG@Tf 12 | 12 | 150 ± 90 | 2 | 50 | |
MNG@Tf 13 d | 8 | 3 | 140 ± 40 | 2 | 22 |
a Ratio based on mass shift detected by MALDI-TOF-MS; b Hydrodynamic diameter obtained through NTA; c Concentration obtained through Bradford protein assay; d N3-tPG-N3 with Mw = 15 kDa. For all other MNGs the polymer network N3-tPG-N3 with Mw = 5 kDa was used.