Table 1.
Standard Run | Independent Variables | |||
---|---|---|---|---|
X1 | X2 | X3 | X4 | |
1 | A | − | − | − |
2 | B | − | − | − |
3 | A | + | − | − |
4 | B | + | − | − |
5 | A | − | + | − |
6 | B | − | + | − |
7 | A | + | + | − |
8 | B | + | + | − |
9 | A | − | − | + |
10 | B | − | − | + |
11 | A | + | − | + |
12 | B | + | − | + |
13 | A | − | + | + |
14 | B | − | + | + |
15 | A | + | + | + |
16 | B | + | + | + |
17 | A | 0 | 0 | 0 |
18 | B | 0 | 0 | 0 |
19 | A | 0 | 0 | 0 |
20 | B | 0 | 0 | 0 |
Factor | − | 0 | + | |
X1 | Substrate | A: Mucin disk | B: Oral pig mucosal | |
X2 | Force (N) | 0.03 | 0.065 | 0.10 |
X3 | Speed (mm/s) | 1.00 | 5.50 | 10.0 |
X4 | Time (s) | 30.0 | 75.0 | 120.0 |