Figure 7.
In vitro release profiles of diclofenac sodium (DCNa) from chitosan hydrogels in acetate buffer solution at pH 5.5 at 37 °C. Data were obtained from UV-Vis spectroscopy at 280 nm and reported as mean ± S.D from five independent experiments. (a) Effect of degree of cross-linking from non-cross-linked samples to 15% of cross-linked (CTS concentration 3%; DCNa concentration: 1%). (b) Effect of CTS concentration from 2% to 4% CTS concentration (degree of cross-linking: 10%; DCNa concentration: 1%). (c) Effect of DCNa concentration from 0.5% to 2% DCNa concentration (degree of cross-linking: 10%; CTS concentration: 3%).