Figure 1.

Budesonide attenuated the histopathological injury induced by LPS in mice. C57BL/6 mice received LPS administration (5 mg/kg, i.t.) with/without budesonide pretreatment (0.5 mg/kg). Twelve hours after LPS injection, histopathological changes were observed using HE staining (a). Lung injury scores were used to semiquantitatively evaluate the histopathological injury (b). Data were expressed as means ± standard deviations (n = 8). ^∗∗P < 0.01 compared with the control group and ^#P < 0.05 compared with the ALI group.