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CM derived from SD-MSCs induces tube formation in HUVEC cultures. (a) Representative images of the tubule-like structures that appeared in each condition (200 µm scale bar). Analysis of the number of (b) meshes and (c) nodes formed after 12 h for the CM treatment (CM), positive controls (Pos; EBM-2 fully supplemented, as described in M&M) or negative controls (Neg; EBM-2 without any supplementation). ***p < 0.001; ****p < 0.0001.
