Scheme 1.
Synthesis of 1-deaza- and 3-deazaadenine derivatives 2a and 2b. Reagents and conditions: i) TMSBr, pyridine, rt; then (L)-NH2CH(Bn)COOiPr·HCl, PPh3, Aldrithiol-2, pyridine, Et3N, 70 °C.
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