FIGURE 5.

Vitamin C 7% vs. vehicle inverse silicon mean Delta E evolution in time for Caucasian population—The vehicle, known to have no effect against ultraviolet (UV), illustrates the skin reaction under the exposures. Pigmentation increases in an incremental manner after each exposure until 7 points of Delta E at 24 hours after the last exposure. Then, pigmentation slightly decreases until the end of the study, without recovering to the initial level. Vitamin C 7% demonstrates efficacy during the increase of pigmentation after each exposure. Then, vitamin C does not have any effect during the natural decreasing of pigmentation. The same comportment is observed in Chinese skin and for the other effective concentrations (10%, 5%, and 3%).