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Profile of in vivo arginine metabolism in piglets of different gestational age. The flux of citrulline (A), arginine (B), and nitric oxide (C) was quantified during total parenteral nutrition (TPN) feeding as well during the necrotizing enterocolitis protocol (D, E, and F for citrulline, arginine, and nitric oxide, respectively). Bars are means ± SE. *P < 0.05. Data analyzed by one-way ANOVA and Tukey’s post hoc test. NS, not significant.
