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. 2019 Mar 8;12:1929–1936. doi: 10.2147/OTT.S194463

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© 2019 Cen et al. This work is published and licensed by Dove Medical Press Limited

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STXBP5-AS1 inhibits the PI3K/AKT signaling pathway in GC cells.

Notes: (A, B) Western blot was conducted to examine the association of STXBP5-AS1 and p-AKT1. Significant reduction in p-AKT1 level was observed in pcDNA STXBP5-AS1 groups compared to groups transfected with pcDNA 3.1. Then, the increase in p-AKT1 was found in the si-STXBP5-AS1 group compared to the si-NC group.

Abbreviations: GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GC, gastric cancer; NC, negative control; si, small interfering RNA.