Figure 4.
MYBL2 silencing inhibited growth and tumor-progression ability of ESCC in vivo.
Notes: (A) Representative images of tumors from nude mice implanted with either MYBL2-knockdown or control EC9706 cells. Graphs show tumor growth and average tumor weights. *P<0.05, **P<0.01, based on Student’s t-test. (B, C) MYBL2, Ki67, cyclin B1, and CDK1 expression levels in harvested tumor tissue were determined by immunohistochemistry assay. Graphs show relative expression of MYBL2 Ki67, cyclin B1, and CDK1 in tumor tissue (means ± SD, n=3; **P<0.01).
Abbreviation: ESCC, esophageal squamous-cell carcinoma.