Fig 3. Hazard ratios (HRs) and 95% confidence intervals (CIs) comparing outcomes for authorized generic (AG) versus brand initiators and generic versus brand initiators after 1:1 propensity score matching in each database.

The outcome for amlodipine tablets, amlodipine-benazepril capsules, and quinapril tablets was a composite endpoint comprising hospitalizations for myocardial infarction, ischemic stroke, or coronary revascularization procedures. The outcome for alendronate tablets and calcitonin salmon nasal spray was a composite non-vertebral fracture endpoint comprising humerus, wrist, hip, or pelvis fractures. The outcome for escitalopram tablets and sertraline tablets was hospitalization with a psychiatric condition as the principal discharge diagnosis code. The outcome for glipizide extended release (ER) tablets was initiation of insulin during the follow-up period.