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Evaluation of the effects of premature stimulation on the human atrial action potential (AP) waveforms in sinus rhythm (SR) conditions. In the SR baseline model, Ca2+-independent transient outward K+ current (Ito) is generated by Kv4.3 (A); results are also shown after a 50% switch of Kv1.4 for Kv4.3 (B). In both A and B, b–e show the same Ca2+ and K+ currents that are shown in Fig. 3. See results for further information and explanation.
