Table 1. Characteristics associated with Medical Care Interruption (MCI) at the time of HIV diagnosis of patients seeking HIV care in the infectious diseases department of the Bichat hospital, Paris, between January 2010 and May 2016.
All N = 4,796 |
Regular follow-up (N = 4,179) |
MCI ≥18 months (N = 617) |
|
---|---|---|---|
Age at HIV diagnosis (years) | |||
≤30 | 1,855 (39%) | 1,603 (38%) | 252 (41%) |
[31–45] | 2,275 (47%) | 2,004 (48%) | 271 (44%) |
>45 | 666 (14%) | 572 (14%) | 94 (15%) |
Yeara of enrollment in care | |||
<2002 | 2,041 (43%) | 1,800 (43%) | 241 (39%) |
[2002–2006[ | 930 (19%) | 797 (19%) | 133 (22%) |
[2006–2011[ | 1,064 (22%) | 925 (22%) | 139 (23%) |
[2011–2013[ | 571 (12%) | 494 (12%) | 77 (12%) |
≥2013 | 190 (4%) | 163 (4%) | 27 (4%) |
Sex | |||
Male | 3,041 (63%) | 2,633 (63%) | 408 (66%) |
Female | 1,755 (37%) | 1,546 (37%) | 209 (34%) |
Country of birth | |||
France | 1,824 (38%) | 1,568 (38%) | 256 (41%) |
Sub-Saharan Africa | 1,916 (40%) | 1,695 (40%) | 221 (36%) |
Other countries or unknownb | 1,056 (22%) | 916 (22%) | 140 (23%) |
Residence | |||
Ile-de-France | 2,234 (46%) | 1,978 (47%) | 256 (41%) |
Paris (except the 18th arr.) | 1,610 (34%) | 1,393 (33%) | 217 (36%) |
18th arrondissement of Paris | 552 (12%) | 471 (11%) | 81 (13%) |
Other areas | 285 (6%) | 248 (7%) | 37 (6%) |
No available postal code | 115 (2%) | 89 (2%) | 26 (4%) |
Primary care physicianc | |||
Yes | 3,648 (76%) | 2,359 (56%) | 283 (46%) |
No | 1,148 (24%) | 1,820 (44%) | 334 (54%) |
HIV transmission group | |||
Men who have sex with men | 1,462 (31%) | 1,290 (31%) | 172 (28%) |
Heterosexual men and women | 2,314 (48%) | 2,032 (49%) | 282 (46%) |
People who inject drugs | 257 (5%) | 218 (5%) | 39 (6%) |
Other or no data availabled | 763 (16%) | 639 (15%) | 124 (20%) |
AIDSe at HIV diagnosis | |||
Yes | 367 (8%) | 326 (8%) | 41 (7%) |
No | 4,429 (92%) | 3,853 (92%) | 576 (93%) |
Hepatitis B coinfection | |||
Yes | 269 (6%) | 240 (6%) | 29 (5%) |
No | 4,527 (94%) | 3,939 (94%) | 588 (95%) |
Hepatitis C coinfection | |||
Yes | 269 (6%) | 243 (6%) | 26 (4%) |
No | 4,527 (94%) | 3,936 (94%) | 591 (96%) |
HIV viral load at enrollment (copies/mL)f | |||
≤1,000 | 1,294 (27%) | 1,114 (27%) | 180 (29%) |
1,001–10,000 | 736 (16%) | 625 (15%) | 111 (18%) |
10,001–100,000 | 1,492 (31%) | 1,331 (32%) | 161 (26%) |
>100,000 | 1,225 (26%) | 1,086 (26%) | 139 (23%) |
CD4 count at enrollment (cells/mm3) | |||
≤350 | 2,348 (49%) | 2,060 (49%) | 288 (47%) |
>350 | 2,448 (51%) | 2,119 (51%) | 329 (53%) |
Time period before first visitg | |||
≤6 months | 3,165 (66%) | 2,882 (69%) | 368 (60%) |
>6 months | 1,631 (34%) | 1,382 (31%) | 249 (40%) |
Time between first visit and first ARTh | |||
≤12 months | 2,293 (49%) | 2,054 (49%) | 239 (39%) |
>12 months | 2,359 (51%) | 2,053 (49%) | 306 (50%) |
MCI: Medical Care Interruption
aYear of enrolment are presented in classes corresponding to years of different HIV treatment initiation guidelines. In France, it was recommended to initiate ART under 200 CD4/mm3 in 2002, <350 CD4/mm3 in 2006; <500 CD4/mm3 in 2011 and regardless of CD4 count in 2013.
bThe country of birth was missing for 73 participants
cPrimary care physician declared by the patient, written in the computer file, to whom medical records from the clinic are sent
dThe HIV transmission group information was missing for 587 participants
eAIDS: acquired immune deficiency syndrome defined by using the CDC classification
fThe viral load data were missing for 49 participants
gTime between HIV diagnosis and first medical visit in or outside the clinic
hART: antiretroviral therapy, prescribed for 4,652 patients by the end of the study period