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. 2019 Mar 13;14(3):e0213526. doi: 10.1371/journal.pone.0213526

Table 1. Characteristics associated with Medical Care Interruption (MCI) at the time of HIV diagnosis of patients seeking HIV care in the infectious diseases department of the Bichat hospital, Paris, between January 2010 and May 2016.

All
N = 4,796
Regular follow-up
(N = 4,179)
MCI
≥18 months
(N = 617)
Age at HIV diagnosis (years)
    ≤30 1,855 (39%) 1,603 (38%) 252 (41%)
    [31–45] 2,275 (47%) 2,004 (48%) 271 (44%)
    >45 666 (14%) 572 (14%) 94 (15%)
Yeara of enrollment in care
    <2002 2,041 (43%) 1,800 (43%) 241 (39%)
    [2002–2006[ 930 (19%) 797 (19%) 133 (22%)
    [2006–2011[ 1,064 (22%) 925 (22%) 139 (23%)
    [2011–2013[ 571 (12%) 494 (12%) 77 (12%)
    ≥2013 190 (4%) 163 (4%) 27 (4%)
Sex
    Male 3,041 (63%) 2,633 (63%) 408 (66%)
    Female 1,755 (37%) 1,546 (37%) 209 (34%)
Country of birth
    France 1,824 (38%) 1,568 (38%) 256 (41%)
    Sub-Saharan Africa 1,916 (40%) 1,695 (40%) 221 (36%)
    Other countries or unknownb 1,056 (22%) 916 (22%) 140 (23%)
Residence
    Ile-de-France 2,234 (46%) 1,978 (47%) 256 (41%)
    Paris (except the 18th arr.) 1,610 (34%) 1,393 (33%) 217 (36%)
    18th arrondissement of Paris 552 (12%) 471 (11%) 81 (13%)
    Other areas 285 (6%) 248 (7%) 37 (6%)
    No available postal code 115 (2%) 89 (2%) 26 (4%)
Primary care physicianc
    Yes 3,648 (76%) 2,359 (56%) 283 (46%)
    No 1,148 (24%) 1,820 (44%) 334 (54%)
HIV transmission group
    Men who have sex with men 1,462 (31%) 1,290 (31%) 172 (28%)
    Heterosexual men and women 2,314 (48%) 2,032 (49%) 282 (46%)
    People who inject drugs 257 (5%) 218 (5%) 39 (6%)
    Other or no data availabled 763 (16%) 639 (15%) 124 (20%)
AIDSe at HIV diagnosis
    Yes 367 (8%) 326 (8%) 41 (7%)
    No 4,429 (92%) 3,853 (92%) 576 (93%)
Hepatitis B coinfection
    Yes 269 (6%) 240 (6%) 29 (5%)
    No 4,527 (94%) 3,939 (94%) 588 (95%)
Hepatitis C coinfection
    Yes 269 (6%) 243 (6%) 26 (4%)
    No 4,527 (94%) 3,936 (94%) 591 (96%)
HIV viral load at enrollment (copies/mL)f
    ≤1,000 1,294 (27%) 1,114 (27%) 180 (29%)
    1,001–10,000 736 (16%) 625 (15%) 111 (18%)
    10,001–100,000 1,492 (31%) 1,331 (32%) 161 (26%)
    >100,000 1,225 (26%) 1,086 (26%) 139 (23%)
CD4 count at enrollment (cells/mm3)
    ≤350 2,348 (49%) 2,060 (49%) 288 (47%)
    >350 2,448 (51%) 2,119 (51%) 329 (53%)
Time period before first visitg
    ≤6 months 3,165 (66%) 2,882 (69%) 368 (60%)
    >6 months 1,631 (34%) 1,382 (31%) 249 (40%)
Time between first visit and first ARTh
    ≤12 months 2,293 (49%) 2,054 (49%) 239 (39%)
    >12 months 2,359 (51%) 2,053 (49%) 306 (50%)

MCI: Medical Care Interruption

aYear of enrolment are presented in classes corresponding to years of different HIV treatment initiation guidelines. In France, it was recommended to initiate ART under 200 CD4/mm3 in 2002, <350 CD4/mm3 in 2006; <500 CD4/mm3 in 2011 and regardless of CD4 count in 2013.

bThe country of birth was missing for 73 participants

cPrimary care physician declared by the patient, written in the computer file, to whom medical records from the clinic are sent

dThe HIV transmission group information was missing for 587 participants

eAIDS: acquired immune deficiency syndrome defined by using the CDC classification

fThe viral load data were missing for 49 participants

gTime between HIV diagnosis and first medical visit in or outside the clinic

hART: antiretroviral therapy, prescribed for 4,652 patients by the end of the study period