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. Author manuscript; available in PMC: 2019 Aug 17.
Published in final edited form as: ACS Chem Biol. 2018 Jul 27;13(8):2179–2189. doi: 10.1021/acschembio.8b00342

Figure 1.

Figure 1

N-glycans are required for IgG1 Fc to bind CD16a. (a) Both IgG and CD16a are N-glycosylated and multiple N-glycans contribute to affinity. (b) Cartoon schematics for the IgG1 Fc and CD16a N-glycans; individual carbohydrate residues are defined in the inset.