Attallah 2013.
Methods | Randomised controlled open‐label trial Duration of the study: unclear |
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Participants | Country: Egypt Population: men with isolated idiopathic athenozospermia, prior to intrauterine insemination (IUI), N = 60 Mean age: unknown, quote "both treatment groups were homogenous at the time of randomisation regarding the type and duration of infertility" Inclusion criteria: couples with idiopathic athenozospermia (progressive motility < 32%) with normal other seminal criteria and normal infertility workup for female partner Exclusion criteria: unclear |
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Interventions | N‐acetylcysteine (NAC) 600 mg (n = 30) versus No treatment (n = 30) Duration of treatment: 12 weeks |
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Outcomes | Sperm concentration, progressive sperm motility, clinical pregnancy rate | |
Notes | Conference abstract, no full text. Attempted to contact authors 04.02.2014, unable to find e‐mail address. Letter posted 12.02.2014 |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Couples were randomised" Not mentioned |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Quote: "Open‐labelled" |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Not mentioned |
Selective reporting (reporting bias) | Unclear risk | Unknown ‐ conference abstract |