Li 2005a.
Methods | Randomised trial Duration: unclear |
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Participants | Country: Eastern China Population: infertile men with oligoasthenospermia, N = 80 Mean age: 29 ± 3.5 (23 to 40) years Inclusion criteria: no smoking or alcohol, any fertility medication needed to be stopped 2 weeks before Exclusion criteria: none |
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Interventions | L‐carnitine 2 g (n = 40) versus Vitamin E 100 mg + Vitamin C 200 mg (n = 40) Duration of treatment: 3 months |
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Outcomes | Seminal parameters, pregnancy rate | |
Notes | Article in Chinese, translated by Shaofu Li 10.11.2008. Attempted to contact author re methods of randomisation, concealment and whether SD or SEs used and whether this is the same trial as Li 2005. Also asked whether there were any data on pregnancy rate. Translator replied 22.09.2009 no pregnancy data were available in the text of the trial |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not mentioned |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Withdrawal: 8 from treatment (n = 32) and 9 from control (n = 31). 21% loss to follow‐up. No ITT |
Selective reporting (reporting bias) | Unclear risk | No protocol available. |