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Stability test of compound 27 in mouse plasma
| Storage Conditions (n= 3) | Spiked conc. (ng/ml) | Determined conc. (ng/ml)±SD | Recovery (%) |
|---|---|---|---|
| At room temperature for 4 hr | 3 160 |
2.88 ± 0.16 151 ± 5.6 |
96 94.3 |
| At room temperature for 24 hr | 3 160 |
2.76 ± 0.01 151.3 ± 7.8 |
92.0 94.5 |
| Three freeze-thaw cycles | 3 160 |
2.62 ± 0.06 148.3 ± 4.7 |
87.0 92.7 |
| Long-term stability (at −20°C for 30 days) | 3 160 |
2.57± 0.10 144.7 ± 8.5 |
85.6 90.4 |
