Skip to main content
. Author manuscript; available in PMC: 2019 Apr 26.
Published in final edited form as: Mol Psychiatry. 2018 Sep 13;24(5):710–725. doi: 10.1038/s41380-018-0245-8

Figure 3. Chemogenetic activation of Hoxb1-NE neurons reduced heart rate with no effect on body temperature or corticosterone level.

Figure 3.

Physiological measurement data from (a) heart rate (littermate controls vehicle: n=16; littermate controls CNO: n=17; Hoxb1-NE/hM3Dq vehicle: n=6; Hoxb1-NE/hM3Dq CNO: n=6), (b) body temperature (littermate controls vehicle: n=29; littermate controls CNO: n= 29; Hoxb1-NE/hM3Dq vehicle: n=12; Hoxb1-NE/hM3Dq CNO: n=12), and (c) serum corticosterone level (littermate controls vehicle: n=19; littermate controls CNO: n= 20; Hoxb1-NE/hM3Dq vehicle: n=8; Hoxb1-NE/hM3Dq CNO: n=7). Data are mean ± SEM, *P<0.05 vs. Vehicle (unpaired 2-tailed t-test at specific time points following repeated measures ANOVA).