Table 3.
Targets for imperative motor factors of hunger, sexual drive, sleep and thirst on orexinergic neurons located in the lateral hypothalamus.
| Receptor/imperative motor factor | Action on OX neurons | Reference |
| GHS-R/Ghrelin | Excitatory | Mitchell et al., 2001; Toshinai et al., 2003 |
| AR/Testosterone | Excluded | Simerly et al., 1990; Muschkamp et al., 2007 |
| ER/Estrogen | Excitatory | Shughrue et al., 1997; Muschkamp et al., 2007 |
| A1R/Adenosine | Inhibitory | Svennigsson et al., 1997; Thakhar et al., 2002 |
| AT1aR/Angiotensin II | Inhibitory | Yoshida et al., 2012 |
OX, orexinergic; GHS-R, growth hormone secretagogue receptor; AR, androgen receptor; ER, estrogen receptor; A1R, adenosine receptor type 1; AT1AR, angiotensin II receptor type 1A.