Table 1.

Gene expression in aortic and renal tissues.

Treatment Group	Control (n = 7)	LPS (n = 8)	SAA (n = 6)
AORTA
NF-κB	1.0 (0.0)	1.1 (0.1)	1.6 (0.1)*#
TF	1.0 (0.1)	1.2 (0.1)	2.3 (0.4)*#
GPx-1	1.0 (0.1)	1.2 (0.2)	1.3 (0.6)
CAT	1.0 (0.2)	1.1 (0.2)	2.4 (0.6)*#
KIDNEY
GPx-1	1.0 (0.1)	1.0 (0.3)	2.9 (1.2)*#
CAT	1.0 (0.1)	1.3 (0.2)	3.4 (0.6)*#

Mice received vehicle, LPS or SAA every 3 days over 14 days. After a further 2 weeks, mice were euthanized and total mRNA isolated from aortae and kidneys. Corresponding cDNA products were probed for gene expression by RT-PCR. mRNA expression was normalized to β-actin house-keeping gene and arbitrarily assigned a value of 1 and other data expressed relative to this level; data represent means ± (SD).

^*Different to control; P < 0.05.

^#Different to the corresponding LPS group; P < 0.05. 4 samples of kidney homogenate from the SAA-treatment group failed to yield suitable cDNA product for PCR analyses.