Table 3.

WHO classification of post-transplant lymphoproliferative disorders.

PTLD category	Type	EBV status
Early lesions (Non-destructive)	Plasmacytic hyperplasia Infectious mononucleosis-like PTLD Florid hyperplasia	Almost 100%
Polymorphic (Destructive)	Polyclonal and Monoclonal proliferations	>90%
Monomorphic (Destructive)	Monoclonal Non-Hodgkin Lymphomas, including: - Diffuse large B-Cell lymphoma (~60%) - Burkitt lymphoma - Plasma cell myeloma - T-cell lymphoma	Both EBV+ and EBV–(EBV– in 10–48% of cases)
Hodgkin lymphoma (Destructive)	Monoclonal	>90%