Table 2.

Cortical dynamic histomorphometry values of wild-type (Lgals3^+/+), heterozygous (Lgals3^KO/+), and mutant (Lgals3^KO/KO) mice at 24 wk^a

	Females			Males
Variables compared	Wildtype	Heterozygote	Mutant	Wildtype	Heterozygote	Mutant
Ec.MAR/(μm·d-1)	0.69 ± 0.08	0.70 ± 0.06	0.78 ± 0.06	0.66 ± 0.05	0.57 ± 0.05	0.61 ± 0.04
Ec.M.Pm/Ec.Pm	0.65 ± 0.05	0.63 ± 0.05	0.61 ± 0.04	0.70 ± 0.06	0.64 ± 0.05	0.59 ± 0.06
Ec.BFR/(μm2·μm-1 per day)	0.45 ± 0.07	0.45 ± 0.06	0.49 ± 0.06	0.48 ± 0.07	0.37 ± 0.04	0.36 ± 0.04
Ps.MAR/(μm·d-1)	0.61 ± 0.07	0.66 ± 0.04	0.82 ± 0.03*	0.81 ± 0.05	0.75 ± 0.04	0.68 ± 0.06
Ps.M.Pm/Ps.Pm	0.71 ± 0.06	0.73 ± 0.05	0.78 ± 0.05	0.66 ± 0.04	0.63 ± 0.03	0.67 ± 0.05
Ps.BFR/(μm2·μm-1 per day)	0.44 ± 0.06	0.48 ± 0.04	0.64 ± 0.04*	0.54 ± 0.06	0.47 ± 0.03	0.47 ± 0.07

Ec, endocortical; Ps, periosteal; MAR, mineral apposition rate; M.Pm/Pm, mineralizing perimeter/total perimeter; BFR, bone formation rate.

^aValues are expressed as mean ± S.E.M. (n = 7–10). Holm–Sidak post-hoc analysis adjusted P-values relative to wild type; bold values highlight *P < 0.05.