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. 2019 Mar 13;9:4339. doi: 10.1038/s41598-019-39607-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression profiles of different somatostatin receptor (SST) subtypes and CXCR4 chemokine receptor in primary tumors and metastases of gastroenteropancreatic neuroendocrine neoplasms. (A) Percentage of positive cases for different SSTs and CXCR4. Tumors were only considered positive at IRS values ≥3. (B) Box plots of somatostatin receptor (SST) and CXCR4 expression levels (IRS values). Depicted are median values, upper and lower quartiles, minimum and maximum values, and outliers. Outliers are defined as follows: circles: mild outliers; data that fall between 1.5 and 3 times above the upper quartile or below the lower quartile; asterisks: extreme outliers; data that fall more than 3 times above the upper quartile or below the lower quartile.