Table 5.

Effect of coroslic acid on biochemical parameters in diabetic rats.

Parameter	Normal control	Diabetic control	Metformin 160 mg/kg	CA 50 mg/kg	CA 100 mg/kg
FBG(mmol/L)	5.51 ± 1.41	26.37 ± 7.82b	10.47 ± 5.86d	8.25 ± 4.67d	7.21 ± 3.11d
GSP(mmol/L)	0.61 ± 0.11	1.63 ± 0.44b	0.94 ± 0.29d	0.91 ± 0.28d	0.90 ± 0.32d
TC(mmol/L)	2.08 ± 0.41	6.58 ± 1.50	2.59 ± 1.10	2.46 ± 1.15	2.11 ± 0.53
TG(mmol/L)	0.65 ± 0.17	2.71 ± 0.86b	1.09 ± 0.67	0.76 ± 0.23	0.81 ± 0.37
HDL-C(mmol/L)	1.71 ± 0.31	0.84 ± 0.26	1.56 ± 0.40	1.55 ± 0.31	1.77 ± 0.33
LDL-C(mmol/L)	0.49 ± 0.23	3.46 ± 0.81	0.66 ± 0.37	0.71 ± 0.29	1.56 ± 0.40
FFA(μmol/L)	0.51 ± 0.06	1.95 ± 0.21b	0.53 ± 0.10d	1.01 ± 0.15d	0.78 ± 0.17d
SOD(U/ml)	295.6 ± 45.8	188.7 ± 28.4b	291.9 ± 52.2d	248.6 ± 39.5c	249.8 ± 30.8d
MDA(nmol/L)	2.26 ± 0.71	10.83 ± 0.61b	4.48 ± 1.78d	5.51 ± 2.26d	5.12 ± 1.35d

The diabetic rats were orally ingested by coroslic acid (50 or 100 mg/kg) and metformin (100 mg/kg) once a day for 6 weeks. The rats of normal control and diabetic control were administrated with vehicle. All above indexes were analyzed after six weeks conducting. Values are recorded by mean ± S.D. for 9 rats in each group. One-way ANOVA test was applied for comparisons between different groups. ^bP < 0.01 compared with normal control group; ^cP < 0.05 compared with diabetic control group; ^dP < 0.01 compared with diabetic control group.