Table 1.

Echocardiographic analyses of WT and YAP-CHKO mice 7 days after TAC

Data are presented as mean ± S.D. The following abbreviations are used: DSEP WT, diastolic septal wall thickness; LVEDD, left ventricular end diastolic dimension; DPWT, diastolic posterior wall thickness; LVESD left ventricular end systolic dimension; LVEF, left ventricular ejection fraction; %FS, fractional shortening.

	WT		YAP-CHKO
	Sham	TAC	Sham	TAC
n	12	14	12	14
DSEP WT (mm)	0.79 ± 0.05	0.81 ± 0.10	0.77 ± 0.09	0.83 ± 0.09
LVEDD (mm)	3.44 ± 0.30	3.35 ± 0.24	3.58 ± 0.28	3.89 ± 0.29a
DPWT (mm)	0.67 ± 0.07	0.72 ± 0.11	0.73 ± 0.06	0.73 ± 0.12
LVESD (mm)	2.30 ± 0.35	2.26 ± 0.35	2.57 ± 0.44	3.18 ± 0.37
EF (%)	68.4 ± 13.1	66.5 ± 15.4	62.1 ± 12.1	44.2 ± 14.0a,b
%FS (%)	33.12 ± 9.53	32.18 ± 11.23	28.45 ± 7.97	18.27 ± 7.18a,b

^a p < 0.05 versus WT-TAC is shown.

^b p < 0.05 versus YAP-CHKO-SHAM is shown. Statistical analyses were conducted with ANOVA. Post hoc analysis was conducted with Tukey's test.