Table 2.

Hemodynamic measurements of WT and YAP-CHKO mice 7 days after TAC

Data are presented as mean ± S.D. The following abbreviations are used: LVEDP, left ventricular end diastolic pressure; +dP/dt and −dP/dt, change in pressure over time; PG, pressure gradient.

	WT		YAP-CHKO
	Sham	TAC	Sham	TAC
n	10	14	10	14
+dP/dt (mm Hg/s)	7750 ± 1327	5839 ± 1403a	5625 ± 1579b	4964 ± 1397c
−dP/dt (mm Hg/s)	7520 ± 1079	6339 ± 1950	5125 ± 1165b	4732 ± 1908d
LVEDP (mm Hg)	5.58 ± 1.56	12.29 ± 3.29a	7.8 ± 4.5	16.57 ± 5.80d,e
PG (mm Hg)	NA	72.86 ± 24.1	NA	53.14 ± 22.1

^a p < 0.05 versus WT-Sham mice.

^b p < 0.01 versus WT-Sham mice.

^c p < 0.001 versus WT-TAC mice.

^d p < 0.001 versus WT-TAC mice.

^e p < 0.05 versus YAP-CHKO-Sham. Statistical analyses were conducted with ANOVA. Post hoc analysis was conducted with Tukey's test.