Figure 2.

Anticancer drug screening of the MTAM-based HFA system (a) in vitro and in vivo cell culture of H460 and A549 which demonstrated superior cell proliferation within 4 days when cultured using MTAM as a substrate, the growth inhibition of H460 and A549 cells by pemetrexed (b) in vitro or (c) in vivo. (d) Growth inhibition of HT29 cells in the MTAM implanted s.c. in mice. Drugs were administrated once daily by i.p. injection from days 3–7 after implantation (Student’s t-test; P < 0.05).