Figure 1.

Dpep2 was significantly increased in viral myocarditis (VMC). Male BALB/c mice were intraperitoneally injected with 10³ PFU CVB3 and the heart tissues were collected at the indicated time points. Myocarditis severity was evaluated by (A) pathological observation (magnification: 200 ×) and (B) percentage of myocardial inflammation. (C) Myocardial Dpep2 kinetics during CVB3 infection were detected by Western blot. (D) Band intensities were quantified by ImageJ software and normalized to GAPDH. Individual experiments were conducted three times with similar results and the representative data were shown. Data were presented as the means ± S.E.M. ^*p < 0.05; ^***p < 0.001.