Table 4.
Reduction in Plasma TG Levels With Lifestyle and Pharmacological Interventions
| Intervention | Approximate Reduction in Plasma TG Level |
|---|---|
| Lifestyle | |
| Weight loss (38, 132, 133) | 0.27 mg/dL per kg weight loss |
| 5%–10% reduction in initial body weight reduces TG levels by 25% | |
| Dietary modification (38, 134, 135) | 0.18 mmol/L (15.7 mg/dL) reduction in plasma TG levels with a plant-based protein and unsaturated fat–enriched diet |
| 10%–15% reduction in plasma TG levels with Mediterranean diet | |
| Exercise (38) | ≤20% reduction in plasma TG levels with moderate to intense aerobic exercise |
| ∼5% reduction in plasma TG levels with resistance training | |
| Pharmacotherapy | |
| Statins (131) | Dose-dependent reductions in TG of 22%–45% in individuals with baseline TG >250 mg/dL |
| Minimal reduction in TG in individuals with baseline TG <150 mg/dL | |
| Fibrates (15) | 30%–50% |
| Niacin (15) | ≤30% |
| OM3FAs (15) | 30%–50% |