Table 3.
Genotype and allele frequencies of the MTHFD1 G1958A polymorphism in case and control groups
| Genotype | Case(N = 61) | Control(N = 61) | χ2 values | OR | 95%CI | P values |
|---|---|---|---|---|---|---|
| GG | 23(37.7) | 37(60.7) | 1 | |||
| GA | 34(55.7) | 21(34.4) | 6.331 | 2.600 | 1.227~5.529 | 0.012* |
| AA | 4(6.6) | 3(4.9) | 2.145 | 0.440~10.464 | 0.427** | |
| G | 80(65.6) | 95(77.9) | 1 | |||
| A | 42(34.4) | 27(22.1) | 4.547 | 1.847 | 1.047~3.259 | 0.033* |
Note: *P value< 0.05 indicates that the genotype and allele distributions of MTHFD1 G1958A polymorphism exhibit a significant difference between case and control groups
**P value are calculated using Fisher’s exact test