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. 2019 Mar 14;11:49. doi: 10.1186/s13148-019-0648-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — An mQTL affecting gene expression distal to DNAm probe. a Location of genes on chromosome 19 surrounding an mQTL closest to ARHGAP33 and nearby eQTL for IGFLR1(TMEM149). The location of the eQTL gene expression probe is highlighted in purple, the mQTL DNAm probe is highlighted in orange and the mQTL and eQTL SNP is highlighted in green. The arrow indicates the association of the mQTL SNP with expression of the IGFLR1 probe. b Expression of the IGFLR1 probe (ILMN_1786426) in endometrium from women with different genotypes at rs62112162. c Methylation of the cg16569309 probe in endometrium from women with different genotypes at rs62112162. d SMR locus plot showing the endometrial eQTL P values of SNPs for the IGFLR1 probe (ILMN_1786426) (top) and mQTL P values of SNPs from this study for the DNAm probe cg16569309 (bottom)