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. 2019 Mar 13;21:74. doi: 10.1186/s13075-019-1855-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of PGIS in healthy and diseased tendon tissues. a Representative immunohistochemistry staining showing expression of IP receptor and PGIS in tendon tissues. Immunostaining (brown) nuclear counterstain is hematoxylin. Scale bar, 50 μm. b Representative confocal immunofluorescence images showing staining of cell nuclei (POPO1, cyan), CD31 (green), CD34 (red), and PGIS (purple) in diseased Achilles tendon tissues. Scale bar, 20 μm