Table 1.
Clinicopathological characteristics of the testicular germ cell tumor cohort
| Clinicopathological features | TGCT patients (n = 122) |
|---|---|
| Median age, years (IQR) | 28 (24–36) |
| Histological type | |
| Seminoma | 56/122 (45.9%) |
| Embryonal carcinoma | 5/122 (4.1%) |
| Postpubertal-type yolk sac tumor | 0/122 (0%) |
| Choriocarcinoma | 0/122 (0%) |
| Postpubertal-type teratoma | 3/122 (2.5%) |
| Mixed tumor | 58/122 (47.5%) |
| Pathological stage | |
| I | 78/122 (63.9%) |
| II | 23/122 (18.9%) |
| III | 21/122 (17.2%) |
| IGCCCG grouping (for metastatic disease) | |
| Good | 31/44 (70.5%) |
| Intermediate | 6/44 (13.6%) |
| Poor | 7/44 (15.9%) |
| Clinicopathological features | Primary TGCT tumor samples (n = 197) |
|---|---|
| Histological type | |
| Seminoma | 75/197 (38.0%) |
| Embryonal Carcinoma | 39/197 (19.8%) |
| Postpubertal-type yolk sac tumor | 35/197 (17.8%) |
| Choriocarcinoma | 12/197 (6.1%) |
| Postpubertal-type teratoma | 36/197 (18.3%) |
| Clinicopathological features | Metastatic TGCT tumor samples (n = 19) |
|---|---|
| Histological type | |
| Seminoma | 1/19 (5.3%) |
| Embryonal carcinoma | 5/19 (26.3%) |
| Postpubertal-type yolk sac tumor | 3/19 (15.8%) |
| Choriocarcinoma | 1/19 (5.3%) |
| Postpubertal-type teratoma | 9/19 (47.3%) |
| Type of metastasis | |
| Lymph node | 12/19 (63.2%) |
| Visceral | 7/19 (36.8%) |
IGCCCG International Germ Cell Cancer Collaborative Group, IQR interquartile range, TGCT testicular germ cell tumors