Table 3.
Association between different locations of cerebral microbleeds and brain region volumes.
| CMBs vs. no CMBs (94 vs. 433) | Deep/Mixed CMBs vs. no CMBs (50 vs. 433) | Lobar CMBs vs. no CMBs (44 vs. 433) | ||
|---|---|---|---|---|
| Subcortical | ||||
| Hippocampus | Model 1 | −0.030 (0.062) | 0.039 (0.080) | −0.091 (0.085)⁎ |
| Model 2 | −0.029 (0.064) | 0.040 (0.083) | −0.091 (0.086)⁎ | |
| Thalamus | Model 1 | −0.103 (0.105)⁎ | −0.068 (0.134)⁎ | −0.092 (0.144)⁎ |
| Model 2 | −0.105 (0.108)⁎ | −0.070 (0.138)⁎ | −0.094 (0.146)⁎ | |
| Amygdala | Model 1 | −0.029 (0.033) | 0.028 (0.043) | −0.076 (0.046)⁎ |
| Model 2 | −0.032 (0.034) | 0.031 (0.044) | −0.080 (0.047)⁎ | |
| Accumbens | Model 1 | 0.027 (0.015) | 0.059 (0.019) | −0.080 (0.019) |
| Model 2 | 0.020 (0.015) | 0.047 (0.020) | −0.023 (0.019) | |
| Cortical | ||||
| Frontal | Model 1 | −0.019 (2.056) | 0.019 (2.650) | −0.049 (2.900) |
| Model 2 | −0.011 (2.109) | 0.024 (2.731) | −0.039 (2.931) | |
| Parietal | Model 1 | −0.015 (1.686) | 0.015 (2.194) | −0.037 (2.353) |
| Model 2 | −0.005 (1.736) | 0.022 (2.275) | −0.029 (2.390) | |
| Temporal | Model 1 | −0.018 (1.763) | 0.028 (2.276) | −0.054 (2.481) |
| Model 2 | −0.008 (1.812) | 0.038 (2.350) | −0.047 (2.514) | |
| Occipital | Model 1 | −0.016 (0.847) | 0.007 (1.102) | −0.030 (1.184) |
| Model 2 | −0.003 (0.872) | 0.015 (1.142) | −0.017 (1.201) | |
All results are presented as standardized coefficients β (SE).
Model 1 was adjusted for age, sex and TIV; Model 2 was additionally adjusted for smoking, drinking, hypertension, diabetes, and hyperlipidemia based on Model 1.
⁎
P < .05.