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. 2019 Mar 14;13:32. doi: 10.1186/s12918-019-0703-1

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Adaptive responses of circuits. A range of circuits exhibit exact adaptation in a ramp, such as (a) A linear motif with inflow and outflow DR08.M1 (b) A cyclic motif with inflow and outflow DR08.M33 (c) An incoherent feedforrward motif (KR09) (d) An incoherent feedforward motif which can exhibit fold-change detection KI14 (e) An incoherent feedforward motif CO09.M2, which has (opposite) thresholds associated with each leg. (f) A transcritical circuit TC. The respective network motifs are depicted in the inset