Table 4.
Mediation analyses between treatment assignment and physical function and pain
| Outcome | Predictor | Mediator | Indirect effect | Direct effect | Ratio of indirect to direct | Sobel test p value |
|---|---|---|---|---|---|---|
| Change in 6MWT (m) | D+E versus E | aDuration Chg | 0.067 | 0.099 | 0.672 | .0353* |
| bBalance Chg | 0.012 | 0.132 | 0.092 | .5436 | ||
| D+E versus D | Duration Chg | 0.087 | 0.237 | 0.365 | .0196* | |
| Balance Chg | 0.026 | 0.268 | 0.095 | .1508 | ||
| Change in gait speed (m/s) | D+E versus E | Duration Chg | 0.085 | 0.082 | 1.030 | .0083* |
| Balance Chg | 0.041 | 0.102 | 0.396 | .0629 | ||
| D+E versus D | Duration Chg | 0.072 | 0.053 | 1.372 | .0338* | |
| Balance Chg | 0.004 | 0.093 | 0.043 | .7447 | ||
| Change in WOMAC function | D+E versus E | Duration Chg | −0.111 | −0.144 | 0.767 | .0033* |
| Balance Chg | −0.072 | −0.178 | 0.405 | .0187* | ||
| D+E versus D | Duration Chg | −0.175 | −0.049 | 3.603 | .0003* | |
| Balance Chg | −0.095 | −0.091 | 1.038 | .0356* | ||
| Change in WOMAC pain | D+E versus E | Duration Chg | −0.082 | −0.127 | 0.646 | .0170* |
| Balance Chg | −0.040 | −0.169 | 0.239 | .1066 | ||
| D+E versus D | Duration Chg | −0.146 | −0.097 | 1.507 | .0028* | |
| Balance Chg | −0.071 | −0.146 | 0.485 | .0483* |
All predictors and outcomes are standardized. All models adjusted for baseline BMI, gender, and baseline values of the outcome. 6MWT Six-Minute Walk Test; WOMAC Western Ontario McMasters Universities Osteoarthritis Index.
aDuration Chg: Self-efficacy for walking duration.
bBalance Chg: Balance efficacy.
*p < .05.