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. 2018 Apr 4;9(2):227–235. doi: 10.1093/tbm/iby037

Table 4.

Mediation analyses between treatment assignment and physical function and pain

Outcome Predictor Mediator Indirect effect Direct effect Ratio of indirect to direct Sobel test p value
Change in 6MWT (m) D+E versus E aDuration Chg 0.067 0.099 0.672 .0353*
bBalance Chg 0.012 0.132 0.092 .5436
D+E versus D Duration Chg 0.087 0.237 0.365 .0196*
Balance Chg 0.026 0.268 0.095 .1508
Change in gait speed (m/s) D+E versus E Duration Chg 0.085 0.082 1.030 .0083*
Balance Chg 0.041 0.102 0.396 .0629
D+E versus D Duration Chg 0.072 0.053 1.372 .0338*
Balance Chg 0.004 0.093 0.043 .7447
Change in WOMAC function D+E versus E Duration Chg −0.111 −0.144 0.767 .0033*
Balance Chg −0.072 −0.178 0.405 .0187*
D+E versus D Duration Chg −0.175 −0.049 3.603 .0003*
Balance Chg −0.095 −0.091 1.038 .0356*
Change in WOMAC pain D+E versus E Duration Chg −0.082 −0.127 0.646 .0170*
Balance Chg −0.040 −0.169 0.239 .1066
D+E versus D Duration Chg −0.146 −0.097 1.507 .0028*
Balance Chg −0.071 −0.146 0.485 .0483*

All predictors and outcomes are standardized. All models adjusted for baseline BMI, gender, and baseline values of the outcome. 6MWT Six-Minute Walk Test; WOMAC Western Ontario McMasters Universities Osteoarthritis Index.

aDuration Chg: Self-efficacy for walking duration.

bBalance Chg: Balance efficacy.

*p < .05.