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. 2019 Mar 13;17:39. doi: 10.1186/s12951-019-0470-6

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Confocal fluorescence microscopy images showing carboxylated quantum dots localization in MSC culture at different cell cultivation densities. At low cultivation density (5000 cells/cm²; top row), QDs (red) distribute intracellularly and at high cultivation density (20,000 cells/cm²; bottom row), QDs deposit on long cytoplasmic processes attaching cells 1 h (a, e), 3 h (b, f), 6 h (c, g) and 24 h (d, h), respectively, after QDs introduction. Scale bars 15 μm (a–d) and 50 μm (e–h)