Table 2.

Differentially expressed genes in free-floating Porphyromonas gingivalis ATCC 33277 cells either in presence of a growing biofilm or in pure planktonic growth (cutoff ratio ± 1.5-fold change, p-value < 0.05) for the microarray analysis

Open reading framea	Genea	Protein or function	Expression ratio by Microarrayb (SD)
PGN_0181		Fimbrillin-A associated anchor proteins Mfa1 and Mfa2	−1.60 (0.09)
PGN_0183	fimC	Minor component FimC	−1.76 (0.16)
PGN_0493		Heavy-metal-associated domain (Hma)	+ 1.56 (0.03)
PGN_0495		Conserved hypothetical protein	+ 1.73 (0.15)
PGN_0529	batA	Aerotolerance-related membrane protein BatA	−1.62 (0.02)
PGN_0557	hmuR	TonB-dependent receptor HmuR	+ 1.67 (0.13)
PGN_0604		Ferritin	+ 1.78 (0.08)
PGN_0649		Conserved hypothetical protein	+ 1.78 (0.18)
PGN_0780	prtQ	PrtQ, protease	+ 1.84 (0.41)
PGN_0787		Conserved hypothetical protein	+ 1.61 (0.06)
PGN_1058	ftn	Ferritin	+ 1.74 (0.12)
PGN_1093		Conserved hypothetical protein	−1.61 (0.14)
PGN_1206	folD	Methylenetetrahydrofolate dehydrogenase/ cyclohydrolase	+ 1.86 (0.25)
PGN_1312		Probable transcriptional regulator as Arg-repressor	+ 1.85 (0.47)
PGN_1494		Putative oxygen-independent coproporphyrinogen III	+ 2.02 (0.02)
PGN_1534		Hypothetical protein	+ 1.95 (0.28)
PGN_2071	topA	DNA topoisomerase I	+ 2.26 (0.18)
PG_0009		ISPg5 transposase Orf1	+ 1.74 (0.16)
PG_0437		Polysaccharide export protein, BexD/CtrA/VexA family	+ 1.89 (0.42)
PG_0718		Conserved hypothetical protein	+ 1.99 (0.38)
PG_0942		ISPg5 transposase Orf1	+ 1.59 (0.01)
PG_1169		Hypothetical protein	+ 1.93 (0.28)
PG_1403		Rhomboid family protein	+ 1.70 (0.09)
PG_1712		Alpha-1,2-mannosidase family protein	−1.52 (0.02)
PG_1979		Hypothetical protein	+ 1.82 (0.26)
PG_2094		Conserved domain protein	+ 1.91 (0.32)
PG_2130		Hypothetical protein	−1.58 (0.09)
PG_2131		OmpA_C-like	−1.61 (0.04)

^aPutative identification from Genebank. ^b Results of three biological replicates. Expression ratio by Microarray indicates the mean fold expression (SD) of that gene