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. 2019 Mar 14;16:62. doi: 10.1186/s12974-019-1450-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — UA reduced proinflammatory cytokine production in APP/PS1 Mice. a–c IL-1β, IL-6, and TNF-α levels in the cortex and hippocampus were measured by ELISA. d–f The expressions of IL-1β, IL-6, and TNF-α mRNA in the cortex and hippocampus were detected by quantitative RT-PCR. Data are presented as the mean ± SEM, n = 4, *P < 0.05 and **P < 0.01. WT wild-type, UA urolithin A