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. 2019 Mar 12;17:78. doi: 10.1186/s12967-019-1831-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Evolution in body weight gain for sham and abdominal vagal stimulated groups (top left panel). Note that body weight relative to the pre-operative one was significantly reduced in the stimulated group after 45 days of continuous stimulation. This reduction was a consequence of both a diminished daily food intake (top right panel) and an increased resting energy expenditure (bottom right panel). The decreased body weight in the stimulated group was representative of a reduced visceral fat (bottom left panel)