Table 1.
Associations between DAAM1 mRNA expression and clinicopathological characteristics in breast cancer
Characteristics | n | DAAM1a | OR (95% Cl) | P valueb | |
---|---|---|---|---|---|
Low | High | ||||
Tumor size (cm) | |||||
≤ 2 | 61 | 35 | 26 | 1.82 (0.94–3.53) | 0.075 |
> 2 | 87 | 50 | 50 | ||
Unknown | 9 | ||||
Lymph node metastasis | |||||
N0 | 121 | 73 | 48 | 9.43 (3.43–25.95) | < 0.001 |
N1–N3 | 36 | 5 | 31 | ||
Distant metastasis | |||||
M0 | 151 | 78 | 73 | – | 0.039 |
M1 | 6 | 0 | 6 | ||
ER status | |||||
Negative | 51 | 23 | 28 | 0.76 (0.39–1.49) | 0.426 |
Positive | 106 | 55 | 51 | ||
PR status | |||||
Negative | 67 | 31 | 37 | 0.77 (0.41–1.45) | 0.419 |
Positive | 89 | 47 | 42 | ||
Unknown | 1 | ||||
Her-2 status | |||||
Negative | 94 | 45 | 49 | 0.89 (0.47–1.69) | 0.720 |
Positive | 61 | 31 | 30 | ||
Unknown | 2 | ||||
P53 status | |||||
Negative | 105 | 51 | 54 | 0.99 (0.48–2.04) | 0.982 |
Positive | 41 | 20 | 21 | ||
Unknown | 11 | ||||
Ki67 status | |||||
Negative | 33 | 19 | 14 | 1.53 (0.70–3.33) | 0.285 |
Positive | 119 | 56 | 63 | ||
Unknown | 5 |
Italic values indicate significance of P value (P < 0.05)
aThe DAAM1 mRNA expression levels were divided at a cutoff point of 50%
bP value for χ2 test