Table 2.
Clinicopathological characteristics, allelic, and genotypes distribution in breast cancer patients
| Characteristics | n | rs79036859a | OR (95% Cl) | P valueb | |
|---|---|---|---|---|---|
| AA | AG/GG | ||||
| Tumor size (cm) | |||||
| ≤ 2 | 61 | 37 | 24 | 1.20 (0.61–2.33) | 0.599 |
| > 2 | 87 | 49 | 38 | ||
| Unknown | 9 | ||||
| Lymph node metastasis | |||||
| N0 | 121 | 70 | 41 | 3.90 (1.77–8.59) | < 0.001 |
| N1–N3 | 36 | 12 | 24 | ||
| Distant metastasis | |||||
| M0 | 151 | 90 | 61 | 2.95 (0.52–16.62) | 0.200 |
| M1 | 6 | 2 | 4 | ||
| ER status | |||||
| Negative | 51 | 29 | 22 | 0.90 (0.46–1.77) | 0.759 |
| Positive | 106 | 63 | 43 | ||
| PR status | |||||
| Negative | 67 | 38 | 29 | 0.85 (0.45–1.62) | 0.619 |
| Positive | 89 | 54 | 35 | ||
| Unknown | 1 | ||||
| Her-2 status | |||||
| Negative | 94 | 51 | 43 | 0.67 (0.35–1.30) | 0.233 |
| Positive | 61 | 39 | 22 | ||
| Unknown | 2 | ||||
| P53 status | |||||
| Negative | 105 | 63 | 42 | 1.30 (0.63–2.68) | 0.485 |
| Positive | 41 | 22 | 19 | ||
| Unknown | 11 | ||||
| Ki67 status | |||||
| Negative | 33 | 22 | 11 | 1.55 (0.69–3.49) | 0.285 |
| Positive | 119 | 67 | 52 | ||
| Unknown | 5 | ||||
Italic values indicate significance of P value (P < 0.05)
aAA genotype was used as a reference
bP value for χ2 test