Table 3.
Comparisons of demographic and clinical variables between subjects with baseline CDR Global score of 0 and 0.5
| Variables | All sample | Baseline CDR |
Baseline CDR 0 |
Baseline CDR 0.5 |
Baseline CDR 0 |
Baseline CDR 0.5 |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 0.5 | Cognitive stable | Cognitive decline | Cognitive stable | Cognitive decline | Non-completers | Completers | Non-completers | Completers | ||
| Subject, n | 644 | 497 | 147 | 435 | 62 | 101 | 46 | 186 | 311 | 67 | 80 |
| Age, M (SD) | 79.5 (3.6) | 79.4 (3.6) | 79.8 (3.6) | 79.3 (3.6) | 80.2 (3.9) | 79.3 (3.5) | 81.0 (3.6)* | 80.0 (4.2) | 79.0 (3.2)* | 80.3 (4.0) | 79.4 (3.2) |
| Male, % | 41.8 | 39.6 | 49.0* | 40.2 | 35.5 | 51.5 | 43.5 | 37.1 | 41.2 | 55.2 | 43.8 |
| White, % | 77.2 | 77.3 | 76.9 | 79.5 | 61.3* | 76.2 | 78.3 | 71.5 | 80.7* | 68.7 | 83.8* |
| Married, % | 55.9 | 54.3 | 61.2 | 55.2 | 48.4 | 63.4 | 56.5 | 45.7 | 59.5* | 68.7 | 55 |
| Education (y), M (SD) | 15.0(3.1) | 15.0 (3.0) | 14.8 (3.4) | 15.2 (2.9) | 14.0 (3.4)* | 14.8 (3.5) | 14.7 (3.1) | 14.5 (3.0) | 15.3 (2.9)* | 14.1 (3.6) | 15.4 (3.1)* |
| Living with study partners, % | 49.1 | 47.5 | 54.4 | 46.9 | 51.6 | 56.4 | 50 | 41.9 | 50.8 | 62.7 | 47.5 |
| Subject’s CFI at baseline | 2.4 (2.3) | 2.0 (1.9) | 3.8 (2.9)* | 1.9 (1.8) | 2.7 (2.3)* | 3.4 (2.8) | 4.5 (3.1)* | 2.4 (2.1) | 1.8 (1.8)* | 4.5 (3.3) | 3.2 (2.4)* |
| Study partner’s CFI at baseline | 1.5 (2.1) | 1.0 (0.2) | 3.0 (2.9)* | 0.9 (1.4) | 1.6 (2.1)* | 2.8 (2.8) | 3.5 (2.9) | 1.1 (1.6) | 1.0 (1.5) | 3.6 (3.2) | 2.5 (2.5)* |
| CDR-SOB, M (SD) | 0.3 (0.5) | 0.1 (0.2) | 1.0 (0.5)* | 0.1 (0.2) | 0.2 (0.2)* | 1.0 (0.5) | 1.2 (0.5)* | 0.1 (0.2) | 0.1 (0.2) | 1.2 (0.6) | 0.9 (0.5)* |
| mMMSE, M (SD) | 95.3 (3.7) | 95.6 (3.5) | 94.1 (3.9)* | 96.1 (3.2) | 92.2 (3.8)* | 94.7 (3.9) | 92.8 (3.8)* | 94.8 (3.8) | 96.1 (3.2)* | 93.0 (4.4) | 94.9 (3.3) |
| FSCRT, M (SD) | 47.8 (0.5) | 47.8 (0.5) | 47.7 (0.7)* | 47.9 (0.4) | 47.6 (0.8)* | 47.8 (0.5) | 47.5 (0.9)* | 47.8 (0.6) | 47.9 (0.4) | 47.6 (0.8) | 47.8 (0.5) |
| GDS, M (SD) | 1.5 (2.0) | 1.3 (1.8) | 2.4 (2.4)* | 1.2 (1.8) | 1.6 (2.3) | 2.3 (2.3) | 2.7 (2.7) | 1.6 (2.0) | 1.1 (1.7)* | 2.9 (2.4) | 2.0 (2.4)* |
p ≤ 0.05.