Table 4.
The short term (one year) predictability of subject and study partner CFI by baseline CDR
| Subject | All Sample |
CDR = 0 |
CDR = 0.5 |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estimate | 95% CI | Odds Ratio | p | Estimate | 95% CI | Odds Ratio | p | Estimate | 95% CI | Odds Ratio | p | ||||
| CFI in the previous year | 0.227 | 0.131 | 0.323 | 1.255 | <0.001 | 0.296 | 0.166 | 0.426 | 1.344 | <0.001 | 0.098 | −0.026 | 0.222 | 1.103 | 0.122 |
| One year change of CFI | 0.184 | 0.071 | 0.297 | 1.202 | 0.001 | 0.2940 | 0.150 | 0.438 | 1.342 | <0.001 | 0.048 | −0.124 | 0.219 | 1.049 | 0.586 |
| mMMSE score in the previous year | −0.136 | −0.263 | −0.009 | 0.873 | 0.036 | −0.156 | −0.319 | 0.007 | 0.855 | 0.060 | −0.104 | −0.3137 | 0.105 | 0.901 | 0.329 |
| FCSRT score in the previous year | −0.384 | −0.848 | 0.079 | 0.681 | 0.104 | −0.270 | −0.790 | 0.251 | 0.764 | 0.310 | −0.614 | −1.155 | −0.073 | 0.541 | 0.026 |
| Age at baseline | 0.073 | 0.016 | 0.131 | 1.076 | 0.012 | 0.037 | −0.040 | 0.113 | 1.037 | 0.349 | 0.108 | 0.023 | 0.193 | 1.114 | 0.013 |
| Ethnicity | −0.177 | −0.701 | 0.346 | 1.093 | 0.507 | −0.232 | −0.880 | 0.417 | 0.793 | 0.484 | 0.010 | −0.949 | 0.969 | 1.010 | 0.984 |
| Subjects’ language | 0.272 | −0.382 | 0.926 | 1.313 | 0.415 | 0.370 | −0.514 | 1.254 | 1.448 | 0.412 | 0.076 | −1.034 | 1.185 | 1.079 | 0.894 |
| CDR Global score at baseline | 0.571 | 0.109 | 1.033 | 1.770 | 0.015 | ||||||||||
| Study Partner | |||||||||||||||
| CFI in the previous year | 0.174 | 0.101 | 0.247 | 1.190 | <0.001 | 0.237 | 0.151 | 0.322 | 1.267 | <0.001 | 0.100 | −0.028 | 0.228 | 1.105 | 0.125 |
| One year change of CFI | 0.240 | 0.137 | 0.344 | 1.271 | <0.001 | 0.256 | 0.144 | 0.368 | 1.291 | <0.001 | 0.273 | 0.081 | 0.464 | 1.313 | 0.005 |
| mMMSE score in the previous year | −0.127 | −0.254 | 0.001 | 0.881 | 0.053 | −0.159 | −0.322 | 0.005 | 0.853 | 0.057 | −0.106 | −0.314 | 0.103 | 0.900 | 0.321 |
| FCSRT score in the previous year | −0.353 | −0.817 | 0.111 | 0.703 | 0.136 | −0.216 | −0.761 | 0.329 | 0.806 | 0.438 | −0.675 | −1.209 | −0.142 | 0.509 | 0.013 |
| Age at baseline | 0.068 | 0.005 | 0.131 | 1.070 | 0.036 | 0.034 | −0.049 | 0.116 | 1.034 | 0.424 | 0.100 | 0.007 | 0.192 | 1.105 | 0.034 |
| Ethnicity | −0.275 | −0.826 | 0.276 | 0.759 | 0.328 | −0.360 | −1.031 | 0.311 | 0.698 | 0.293 | 0.048 | −0.954 | 1.050 | 1.049 | 0.9252 |
| Subjects’ language | 0.119 | −0.516 | 0.753 | 1.126 | 0.714 | 0.281 | −0.623 | 1.186 | 1.325 | 0.542 | −0.181 | −1.359 | 0.998 | 0.835 | 0.7638 |
| CDR Global score at baseline | 0.558 | 0.092 | 1.024 | 1.747 | 0.019 | ||||||||||
CFI, Cognitive Function Instrument; mMMSE, Modified Mini-Mental State Exam; FCSRT, Free and Cued Selective Reminding Test; CDR, Clinical Dementia Rating.