Table 2.
Adjusted Association Between ATSP and Measures of Physical Function (n = 680)
| Outcome (N = 680) | Gait Speed (m/s) (A) | Perceived Fatigability (RPE) (B) | Time to Walk 400 m (seconds) (C) | Expanded SPPB Score (D) |
|---|---|---|---|---|
| (i) Continuous analysis: Coefficient (SE) | ||||
| Independent variable | ||||
| ASTP (per 0.1 unit) | −0.06*** (0.01) | 0.60*** (0.12) | 16.31*** (2.70) | −0.13*** (0.03) |
| Model R2/Adjusted R2 | .27/.25 | .23/.22 | .45/.44 | .32/.31 |
| (ii) Categorical analysis: odds ratios (95% CI) | ||||
| Independent Variable | Slow Gait (<1.0 m/s) | High Perceived Fatigability (RPE ≥10) | Poor Endurance Performance (>300 s) | Low Functional Performance (<3.07) |
| Lowest tertile | Ref | Ref | Ref | Ref |
| Middle tertile | 1.04 (0.59–1.83) | 1.45 (0.85–2.48) | 2.04* (1.07–3.90) | 1.15 (0.73–1.80) |
| Highest tertile | 1.50 (0.88–2.58) | 2.18* (1.30–3.65) | 2.48** (1.35–4.56) | 2.13** (1.32–3.43) |
Note: Rows show multivariable regression models assessing the (i) continuous and (ii) categorical associations between ASTP and (A) usual gait speed (m/s), (B) perceived fatigability (RPE), (C) time to walk 400 m (seconds), and (D) expanded SPPB score. All models are adjusted for age, sex, race, smoking history, height, weight, and history of cardiovascular disease, stroke, peripheral neuropathy, hypertension, diabetes, cancer, and lower extremity arthritis pain. ASTP = Active-to-Sedentary Transition Probability.
*p < .05, **p < .01, ***p < .001.